Trial Information Background:

Contaminated textiles in hospitals contribute to endogenous, indirect contact, and aerosol transmission of nosocomial related pathogens. Copper oxide impregnated linens have wide-spectrum antimicrobial, anti fungal, and antiviral properties. Our aim was to determine if replacing non-biocidal linens with biocidal copper oxide impregnated linens would reduce the rates of healthcare-associated infections (HAI) in a long-term care ward.


We compared the rates of HAI in two analogous patient cohorts in a head injury care ward over two 6-month parallel periods before (period A) and after (period B) replacing all the regular non-biocidal linens and personnel uniforms with copper oxide impregnated biocidal products.

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During period B, in comparison to period A, there was a 24% reduction in the HAI per 1000 hospitalization-days (p < 0.05), a 47% reduction in the number of fever days (> 38.5 8C) per 1000 hospitalization-days ( p < 0.01), and a 32.8% reduction in total number of days of antibiotic administration per 1000 hospitalization -days (p < 0.0001). Accordingly there was saving of approximately 27% in costs of antibiotics, HAI-related treatments, X-rays, disposables, labor, and laundry, expenses during period B.


The use of biocidal copper oxide impregnated textiles in a long-term care ward may significantly reduce HAI, fever, antibiotic consumption, and related treatment costs.